Barclays Bank of Uganda Limited, commonly known as Barclays Bank Uganda Limited, is a commercial bank in Uganda. It is one of the commercial banks licensed by the Bank of Uganda, the central bank and national banking regulator.

The bank is primarily involved in meeting the banking needs of individuals, small- and medium-sized businesses (SMEs), and large corporations. Before 2006, the bank focused on meeting the banking needs of only large corporations and high-net-worth individuals. That focus was loosened to include SMEs and regular customers.[3] As of December 2014, the bank was the fifth-largest commercial bank in Uganda, with assets valued at UGX:1.4 trillion.[4] At that time, the bank had 136,000 account holders, 42 branches, and 85 ATM outlets and employed 850 staff.